Postdoctoral Position in Solution Dynamics of Protein Kinases - Stony Brook University -New York, USA
From NMR Wiki
posted: Aug 17 2010
A postdoctoral position to study the solution dynamics and structure of protein kinases is available on a NIH funded project (REF#: HS-R-6453-10-08-S).
Our group is interested in how static and dynamic changes of protein structure affect the activity of protein kinases.
We combine X-ray crystallography, NMR and ligand binding kinetics with collaborative molecular dynamic studies (See e.g. ref 1 and 2).
Our research group is located at Stony Brook University in a highly interactive environment with the New York Structural Biology Center and Brookhaven National Laboratory.
How to apply
Interested candidates with a strong background in protein crystallography or protein NMR should email their CV and the names of two references to Markus Seeliger (markus.seeliger@gmail.com).
Markus Seeliger Assistant Professor Department of Pharmacological Sciences Stony Brook University Stony Brook, NY http://www.pharm.stonybrook.edu/seeliger
1.) Shan, Y., Seeliger, M.A., et al. A conserved protonation-dependent switch controls drug binding in the Abl kinase. Proc Natl Acad Sci U S A, 2009. 106(1): p. 139-44.
2.) Seeliger, M.A., et al., Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations. Cancer Res, 2009. 69(6): p. 2384-92.
