MARS

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Mars uses assignment tables containing pseudoresidue spin system records, protein polypeptide sequence, and result of 'psypred' secondary structure prediction program. It also makes use of experimental distributions of aminoacid chemical shifts.

Output of this program is the assignment of pseudoresidue spin systems to protein aminoacids.

Typically, for ~60 aminoacid polypeptide it takes a day to prepare the input table. The program usually generates fairly complete backbone assignment after the first run. Run time depends on the size of protein. (< 2min for chains less then 100 residues)

References

Jung, Y.S., Zweckstetter, M.. Mars-robust automatic backbone assignment of proteins

Journal of Biomolecular NMR 30(1):11--23, 2004
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