Hen Lysozyme

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Early Work

Redfield, C., Dobson, C.M.. Sequential proton NMR assignments and secondary structure of hen egg white lysozyme in solution

Biochemistry 27(1):122--136, 1988

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A detailed example of purely ¹H assignment strategy. Thoughtful sample preparation to selectively show rapidly and slowly exchanging amide protons.

Structure determination

Schwalbe, H., Grimshaw, S.B., Spencer, A., Buck, M., Boyd, J., Dobson, C.M., Redfield, C., Smith, L.J.. {A refined solution structure of hen lysozyme determined using residual dipolar coupling data}

Protein Science 10(4):677, 2001

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