WEFT - water eliminated fourier transform
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- | This experiment<cite>weft</cite> works for molecules whose {{T1}} relaxation time is shorter than {{T1}} of water. | + | This experiment<cite>weft</cite> works for molecules whose {{T1}} relaxation time is shorter than {{T1}} relaxation time of water. |
To achieve water suppression, t<sub>n</sub> is selected so that the Z magnetization of water is zero at the moment the {{90}} pulse is applied. During the same time Z magnetization of the molecule of interest has a chance to fully relax to equilibrium. Both T and t<sub>n</sub> are around 6 s, but should be optimized. | To achieve water suppression, t<sub>n</sub> is selected so that the Z magnetization of water is zero at the moment the {{90}} pulse is applied. During the same time Z magnetization of the molecule of interest has a chance to fully relax to equilibrium. Both T and t<sub>n</sub> are around 6 s, but should be optimized. |
Current revision
This experiment[1] works for molecules whose T1 relaxation time is shorter than T1 relaxation time of water.
To achieve water suppression, tn is selected so that the Z magnetization of water is zero at the moment the 90o pulse is applied. During the same time Z magnetization of the molecule of interest has a chance to fully relax to equilibrium. Both T and tn are around 6 s, but should be optimized.
The article[1] also describes ways of incorporating WEFT into experiments for determination of T1 and T2 relaxation times of macromolecular samples in water.