Postdoctoral Position in Solution Dynamics of Protein Kinases - Stony Brook University -New York, USA

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posted: Aug 17 2010

A postdoctoral position to study the solution dynamics and structure of protein kinases is available on a NIH funded project (REF#: HS-R-6453-10-08-S).

Our group is interested in how static and dynamic changes of protein structure affect the activity of protein kinases.

We combine X-ray crystallography, NMR and ligand binding kinetics with collaborative molecular dynamic studies (See e.g. ref 1 and 2).

Our research group is located at Stony Brook University in a highly interactive environment with the New York Structural Biology Center and Brookhaven National Laboratory.

How to apply

Interested candidates with a strong background in protein crystallography or protein NMR should email their CV and the names of two references to Markus Seeliger (

Markus Seeliger Assistant Professor Department of Pharmacological Sciences Stony Brook University Stony Brook, NY

1.) Shan, Y., Seeliger, M.A., et al. A conserved protonation-dependent switch controls drug binding in the Abl kinase. Proc Natl Acad Sci U S A, 2009. 106(1): p. 139-44.

2.) Seeliger, M.A., et al., Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations. Cancer Res, 2009. 69(6): p. 2384-92.

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