NMR Experiments

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This page is for description of pulse sequences, special applications. Please add references to the original publications, some publications demonstrating use, known implementations on NMR platforms, and set-up instructions.

Isotope filtered experiments (2)

Protein NMR experiments (5)

Contents 1 Homonuclear 1.1 One dimensional 1.2 Two dimensional 2 Heteronuclear 2.1 Two dimensional 2.1.1 Isotope filtered experiments 2.2 Three-dimensional 2.2.1 Isotope filtered experiments 3 Specific to proteins 3.1 General protein experiments 3.2 Aminoacid-specific 4 Links

Homonuclear

One dimensional

1D NOESY

Two dimensional

J-coupling correlations: DQF-COSY (or DQ-COSY), MQ-COSY, TOCSY

NOESY

Heteronuclear

Two dimensional

HX correlation: HSQC

J_HX coupling: JHMBC, HETLOC, pfg,se-HETLOC

NOESY: Heteronuclear NOESY

Isotope filtered experiments

13C-filtered NOESY using swept 13C inversion

Three-dimensional

NOESY-HSQC

TOCSY-HSQC

HCCH-COSY

3D HCN and HNC NOESY

Isotope filtered experiments

X-filtered NOESY-HSQC

X-filtered TOCSY-HSQC

Isotope filtered 13C HMQC NOESY

Specific to proteins

Most of these require ¹³C and ¹⁵N isotope labeled samples. Many experiments in other categories can also be applied to proteins.

General protein experiments

HNCA

HNCO

CBCA(CO)NH

CBCANH

HBHA(CO)NH

Aminoacid-specific

HNN-ST (NMR Experiment)

Links

Carlsberg Laborartory Pulse Sequence Library

BMRB pulse sequence library

CABM NMR pulse sequence library (Rutgers Univ.)

Bax Lab pulse sequences